During the plague of 1630 in Venice, the city experienced a devastating epidemic of bubonic plague that caused a large number of deaths. The plague spread rapidly throughout the city, and it is estimated that approximately one-third of the Venetian population died from the disease. Measures taken to combat the spread of the plague included quarantining the sick, cleaning the streets, and banning public gatherings. Special hospitals were also established, and isolation practices were implemented to control the spread of the disease. This epidemic had a significant impact on Venetian history and society.